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Inspired by websites such as (for Boss effects pedals) and Disco Freq's FX site (listing almost every pedal ever made), our goal is to become a comprehensive resource for all U. A.-made DOD FX-series pedals (and related accessories), featuring notes on design and cosmetic changes, a guide to dating your DOD pedal by serial number, and related literature.
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► Mechanisms of action involve opioid receptors and monoaminergic systems.
► There are potential medical applications for mitragynine analogues.
Kratom as well as its main alkaloid, mitragynine, currently spreads around the world.
Thus, addiction potential and adverse health consequences are becoming an important issue for health authorities.
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There is also evidence from experimental animal models supporting analgesic, muscle relaxant, anti-inflammatory as well as strong anorectic effects.